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MicroRNA-744 Inhibits Proliferation of Bronchial Epithelial Cells by Regulating Smad3 Pathway via Targeting Transforming Growth Factor-β1 (TGF-β1) in Severe Asthma

BACKGROUND: Bronchial epithelial cells proliferation plays a pivotal role in airway remodeling in children with severe asthma. MicroRNAs (miRNAs) have gained great attention for many diseases, including asthma. The purpose of this study was to explore the mechanisms that underlie miR-744 modulating...

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Detalles Bibliográficos
Autores principales: Huang, Han, Lu, Hongxia, Liang, Lihong, Zhi, Yueli, Huo, Beibei, Wu, Linlin, Xu, Liping, Shen, Zhaobo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441316/
https://www.ncbi.nlm.nih.gov/pubmed/30903795
http://dx.doi.org/10.12659/MSM.912412