Generation of Isogenic Controls for In Vitro Disease Modelling of X-Chromosomal Disorders

Generation of proper controls is crucial in induced pluripotent stem cell (iPSC) studies. X-chromosomal disorders offer the potential to develop isogenic controls due to random X-chromosomal inactivation (XCI). However, the generation of such lines is currently hampered by skewed X-inactivation in f...

Descripción completa

Detalles Bibliográficos
Autores principales: Hinz, Lisa, Hoekstra, Stephanie D., Watanabe, Kyoko, Posthuma, Danielle, Heine, Vivi M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441401/
https://www.ncbi.nlm.nih.gov/pubmed/30421281
http://dx.doi.org/10.1007/s12015-018-9851-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441401/
https://www.ncbi.nlm.nih.gov/pubmed/30421281
http://dx.doi.org/10.1007/s12015-018-9851-8

Ejemplares similares