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Generation of Isogenic Controls for In Vitro Disease Modelling of X-Chromosomal Disorders

Generation of proper controls is crucial in induced pluripotent stem cell (iPSC) studies. X-chromosomal disorders offer the potential to develop isogenic controls due to random X-chromosomal inactivation (XCI). However, the generation of such lines is currently hampered by skewed X-inactivation in f...

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Detalles Bibliográficos
Autores principales:	Hinz, Lisa, Hoekstra, Stephanie D., Watanabe, Kyoko, Posthuma, Danielle, Heine, Vivi M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441401/ https://www.ncbi.nlm.nih.gov/pubmed/30421281 http://dx.doi.org/10.1007/s12015-018-9851-8

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