JAM3 functions as a novel tumor suppressor and is inactivated by DNA methylation in colorectal cancer

PURPOSE: JAM3, an adhesion and transmigration regulatory element, is abundantly expressed in intestinal epithelial cells. However, its expression and function in colorectal cancer (CRC) remain unknown. In this study, we explored its epigenetic mechanism and biological role in CRC. PATIENTS AND METHO...

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Detalles Bibliográficos
Autores principales: Zhou, Dan, Tang, Weiwei, Zhang, Yun, An, Han-Xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441464/
https://www.ncbi.nlm.nih.gov/pubmed/30988641
http://dx.doi.org/10.2147/CMAR.S189937

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441464/
https://www.ncbi.nlm.nih.gov/pubmed/30988641
http://dx.doi.org/10.2147/CMAR.S189937

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