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JAM3 functions as a novel tumor suppressor and is inactivated by DNA methylation in colorectal cancer
PURPOSE: JAM3, an adhesion and transmigration regulatory element, is abundantly expressed in intestinal epithelial cells. However, its expression and function in colorectal cancer (CRC) remain unknown. In this study, we explored its epigenetic mechanism and biological role in CRC. PATIENTS AND METHO...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Dove Medical Press
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441464/ https://www.ncbi.nlm.nih.gov/pubmed/30988641 http://dx.doi.org/10.2147/CMAR.S189937 |