Antimycin A-Induced Mitochondrial Damage Causes Human RPE Cell Death despite Activation of Autophagy

Mitochondrial dysfunction has been implicated in a wide variety of degenerative diseases, including age-related macular degeneration. Damage to mitochondria and mitochondrial DNA accumulates with age in the postmitotic retinal pigment epithelium (RPE), which could lead to RPE cell death and trigger...

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Detalles Bibliográficos
Autores principales: Hytti, Maria, Korhonen, Eveliina, Hyttinen, Juha M. T., Roehrich, Heidi, Kaarniranta, Kai, Ferrington, Deborah A., Kauppinen, Anu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441541/
https://www.ncbi.nlm.nih.gov/pubmed/31007832
http://dx.doi.org/10.1155/2019/1583656

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441541/
https://www.ncbi.nlm.nih.gov/pubmed/31007832
http://dx.doi.org/10.1155/2019/1583656

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