Membrane transporter data to support kinetically-informed chemical risk assessment using non-animal methods: Scientific and regulatory perspectives

Humans are continuously exposed to low levels of thousands of industrial chemicals, most of which are poorly characterised in terms of their potential toxicity. The new paradigm in chemical risk assessment (CRA) aims to rely on animal-free testing, with kinetics being a key determinant of toxicity w...

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Detalles Bibliográficos
Autores principales: Clerbaux, Laure-Alix, Paini, Alicia, Lumen, Annie, Osman-Ponchet, Hanan, Worth, Andrew P., Fardel, Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441651/
https://www.ncbi.nlm.nih.gov/pubmed/30856453
http://dx.doi.org/10.1016/j.envint.2019.03.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441651/
https://www.ncbi.nlm.nih.gov/pubmed/30856453
http://dx.doi.org/10.1016/j.envint.2019.03.003

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