Hypoxia as a barrier to immunotherapy in pancreatic adenocarcinoma

Pancreatic ductal adenocarcinoma (PDA) is a lethal disease with limited response to cytotoxic chemoradiotherapy, as well as newer immunotherapies. The PDA tumor microenvironment contains infiltrating immune cells including cytotoxic T cells; however, there is an overall immunosuppressive milieu. Hyp...

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Detalles Bibliográficos
Autores principales: Daniel, S. K., Sullivan, K. M., Labadie, K. P., Pillarisetty, V. G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441665/
https://www.ncbi.nlm.nih.gov/pubmed/30931508
http://dx.doi.org/10.1186/s40169-019-0226-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441665/
https://www.ncbi.nlm.nih.gov/pubmed/30931508
http://dx.doi.org/10.1186/s40169-019-0226-9

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