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IGF-axis confers transformation and regeneration of fallopian tube fimbria epithelium upon ovulation

BACKGROUND: The fallopian tube fimbria is regarded as the main tissue of origin and incessant ovulation as the main risk factor of ovarian high-grade serous carcinoma. Previously, we discovered the tumorigenesis activity of human ovulatory follicular fluid (FF) upon injection to the mammary fat pad...

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Detalles Bibliográficos
Autores principales: Hsu, Che-Fang, Huang, Hsuan-Shun, Chen, Pao-Chu, Ding, Dah-Ching, Chu, Tang-Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441876/
https://www.ncbi.nlm.nih.gov/pubmed/30852161
http://dx.doi.org/10.1016/j.ebiom.2019.01.061