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TARBP2‐mediated destabilization of Nanog overcomes sorafenib resistance in hepatocellular carcinoma

Hepatocellular carcinoma (HCC) is a lethal human malignancy and a leading cause of cancer‐related death worldwide. Patients with HCC are often diagnosed at an advanced stage, and the prognosis is usually poor. The multikinase inhibitor sorafenib is the first‐line treatment for patients with advanced...

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Detalles Bibliográficos
Autores principales: Lai, Hui‐Huang, Li, Chih‐Wei, Hong, Chih‐Chen, Sun, Hung‐Yu, Chiu, Ching‐Feng, Ou, Da‐Liang, Chen, Pai‐Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441883/
https://www.ncbi.nlm.nih.gov/pubmed/30657254
http://dx.doi.org/10.1002/1878-0261.12449