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Anti-tumor necrosis factor α therapy associates to type 17 helper T lymphocytes immunological shift and significant microbial changes in dextran sodium sulphate colitis

BACKGROUND: Anti-tumor necrosis factor α (TNFα) represents the best therapeutic option to induce mucosal healing and clinical remission in patients with moderate-severe ulcerative colitis. On the other side gut microbiota plays a crucial role in pathogenesis of ulcerative colitis but few information...

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Detalles Bibliográficos
Autores principales: Petito, Valentina, Graziani, Cristina, Lopetuso, Loris R, Fossati, Marco, Battaglia, Alessandra, Arena, Vincenzo, Scannone, Domenico, Quaranta, Gianluca, Quagliariello, Andrea, Del Chierico, Federica, Putignani, Lorenza, Masucci, Luca, Sanguinetti, Maurizio, Sgambato, Alessandro, Gasbarrini, Antonio, Scaldaferri, Franco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441917/
https://www.ncbi.nlm.nih.gov/pubmed/30948910
http://dx.doi.org/10.3748/wjg.v25.i12.1465