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Exploiting DNA repair defects in colorectal cancer

Colorectal cancer (CRC) is the third leading cause of cancer‐related deaths worldwide. Therapies that take advantage of defects in DNA repair pathways have been explored in the context of breast, ovarian, and other tumor types, but not yet systematically in CRC. At present, only immune checkpoint bl...

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Detalles Bibliográficos
Autores principales: Reilly, Nicole M., Novara, Luca, Di Nicolantonio, Federica, Bardelli, Alberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441925/
https://www.ncbi.nlm.nih.gov/pubmed/30714316
http://dx.doi.org/10.1002/1878-0261.12467