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Bcl‐2 inhibitors enhance FGFR inhibitor‐induced mitochondrial‐dependent cell death in FGFR2‐mutant endometrial cancer
Endometrial cancer is the most commonly diagnosed gynaecological malignancy. Unfortunately, 15–20% of women demonstrate persistent or recurrent tumours that are refractory to current chemotherapies. We previously identified activating mutations in fibroblast growth factor receptor 2 (FGFR2) in 12% (...
Päätekijät: | , , , , , , , , |
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Aineistotyyppi: | Online Artikkeli Teksti |
Kieli: | English |
Julkaistu: |
John Wiley and Sons Inc.
2019
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Aiheet: | |
Linkit: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441928/ https://www.ncbi.nlm.nih.gov/pubmed/30537101 http://dx.doi.org/10.1002/1878-0261.12422 |