Structure-Based in Silico Screening Identifies a Potent Ebolavirus Inhibitor from a Traditional Chinese Medicine Library

[Image: see text] Potent Ebolavirus (EBOV) inhibitors will help to curtail outbreaks such as that which occurred in 2014–16 in West Africa. EBOV has on its surface a single glycoprotein (GP) critical for viral entry and membrane fusion. Recent high-resolution complexes of EBOV GP with a variety of a...

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Detalles Bibliográficos
Autores principales: Shaikh, Faraz, Zhao, Yuguang, Alvarez, Luis, Iliopoulou, Maria, Lohans, Christopher, Schofield, Christopher J., Padilla-Parra, Sergi, Siu, Shirley W. I., Fry, Elizabeth E., Ren, Jingshan, Stuart, David I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441942/
https://www.ncbi.nlm.nih.gov/pubmed/30785281
http://dx.doi.org/10.1021/acs.jmedchem.8b01328

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441942/
https://www.ncbi.nlm.nih.gov/pubmed/30785281
http://dx.doi.org/10.1021/acs.jmedchem.8b01328

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