Fatty acid 2-hydroxylation inhibits tumor growth and increases sensitivity to cisplatin in gastric cancer

BACKGROUND: Most gastric cancers are diagnosed at an advanced or metastatic stage with poor prognosis and survival rate. Fatty acid 2-hydroxylase (FA2H) with high expression in stomach generates chiral (R)-2-hydroxy FAs ((R)-2-OHFAs) and regulates glucose utilization which is important for cell prol...

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Detalles Bibliográficos
Autores principales: Yao, Yizhou, Yang, Xiaoqin, Sun, Liang, Sun, Shishuo, Huang, Xiaoheng, Zhou, Diyuan, Li, Tingting, Zhang, Wei, Abumrad, Nada A., Zhu, Xinguo, He, Songbing, Su, Xiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Research paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441949/
https://www.ncbi.nlm.nih.gov/pubmed/30738828
http://dx.doi.org/10.1016/j.ebiom.2019.01.066

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441949/
https://www.ncbi.nlm.nih.gov/pubmed/30738828
http://dx.doi.org/10.1016/j.ebiom.2019.01.066

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