Cargando…

Fatty acid 2-hydroxylation inhibits tumor growth and increases sensitivity to cisplatin in gastric cancer

BACKGROUND: Most gastric cancers are diagnosed at an advanced or metastatic stage with poor prognosis and survival rate. Fatty acid 2-hydroxylase (FA2H) with high expression in stomach generates chiral (R)-2-hydroxy FAs ((R)-2-OHFAs) and regulates glucose utilization which is important for cell prol...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yao, Yizhou, Yang, Xiaoqin, Sun, Liang, Sun, Shishuo, Huang, Xiaoheng, Zhou, Diyuan, Li, Tingting, Zhang, Wei, Abumrad, Nada A., Zhu, Xinguo, He, Songbing, Su, Xiong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2019
Materias:	Research paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441949/ https://www.ncbi.nlm.nih.gov/pubmed/30738828 http://dx.doi.org/10.1016/j.ebiom.2019.01.066

Ejemplares similares

Roux-en-Y reconstruction alleviates radical gastrectomy-induced colitis via down-regulation of the butyrate/NLRP3 signaling pathway
por: Yao, Yizhou, et al.
Publicado: (2022)

Glucose Transporter-1 Cooperating with AKT Signaling Promote Gastric Cancer Progression
por: Zhou, Diyuan, et al.
Publicado: (2020)

DAB2IP decreases cell growth and migration and increases sensitivity to chemotherapeutic drugs in colorectal cancer
por: Wu, Guanting, et al.
Publicado: (2021)

DAB2IP Downregulation Enhances the Proliferation and Metastasis of Human Gastric Cancer Cells by Derepressing the ERK1/2 Pathway
por: Sun, Liang, et al.
Publicado: (2018)

Erratum to “DAB2IP Downregulation Enhances the Proliferation and Metastasis of Human Gastric Cancer Cells by Derepressing the ERK1/2 Pathway”
por: Sun, Liang, et al.
Publicado: (2020)

Prognostic and clinicopathological value of FoxM1 expression in colorectal cancer: A systematic review and meta-analysis
por: Yao, Yizhou, et al.
Publicado: (2018)

Laparoscopic proctectomy for rectal cancer in an automated peritoneal dialysis patient: A case report
por: Li, Hao, et al.
Publicado: (2020)

Arenobufagin increases the sensitivity of gastric cancer to cisplatin via alkaliptosis
por: Liu, Chengwei, et al.
Publicado: (2023)

TBK1 Facilitates GLUT1-Dependent Glucose Consumption by suppressing mTORC1 Signaling in Colorectal Cancer Progression
por: Zhou, Diyuan, et al.
Publicado: (2022)

Downregulation of LINC01857 Increases Sensitivity of Gastric Carcinoma Cells to Cisplatin
por: Chen, Yun, et al.
Publicado: (2022)

STING promotes proliferation and induces drug resistance in colorectal cancer by regulating the AMPK-mTOR pathway
por: Yao, Huihui, et al.
Publicado: (2022)

2-Hydroxylated fatty acids as candidates of novel drugs to promote chemosensitivity of gastric cancer
por: Tsuboi, Kazuhito
Publicado: (2019)

The prevention of cisplatin-induced renal dysfunction by hydroxyl-containing dithiocarbamates.
por: Reznik, L. V., et al.
Publicado: (1991)

YAP promotes the proliferation and migration of colorectal cancer cells through the Glut3/AMPK signaling pathway
por: Jiang, Linhua, et al.
Publicado: (2021)

Retracted: Downregulation of LINC01857 Increases Sensitivity of Gastric Carcinoma Cells to Cisplatin
por: Methods in Medicine, Computational and Mathematical
Publicado: (2023)

The ATR inhibitor VE-821 increases the sensitivity of gastric cancer cells to cisplatin
por: Su, Haochen, et al.
Publicado: (2023)

Understanding segregation processes in SAMs formed by mixtures of hydroxylated and non-hydroxylated fatty acids
por: Bueno, Otto V. M., et al.
Publicado: (2019)

Regulation of AMPK Activation by CD36 Links Fatty Acid Uptake to β-Oxidation
por: Samovski, Dmitri, et al.
Publicado: (2015)

Formulation and characterization of cisplatin-loaded hydroxyl functionalized single-walled carbon nanotubes for targeting gastric cancer stem cells
por: Sravani, A.N.K.V., et al.
Publicado: (2023)

Loss of AKR1B10 promotes colorectal cancer cells proliferation and migration via regulating FGF1-dependent pathway
por: Yao, Yizhou, et al.
Publicado: (2020)

Downregulation of Enhancer of Zeste Homolog 2 (EZH2) is essential for the Induction of Autophagy and Apoptosis in Colorectal Cancer Cells
por: Yao, Yizhou, et al.
Publicado: (2016)

Homologous electron transport components fail to increase fatty acid hydroxylation in transgenic Arabidopsis thaliana
por: Wayne, Laura L., et al.
Publicado: (2013)

The Association of Aberrant Expression of FGF1 and mTOR-S6K1 in Colorectal Cancer
por: Duan, Tinghui, et al.
Publicado: (2021)

Corrigendum: The Association of Aberrant Expression of FGF1 and mTOR-S6K1 in Colorectal Cancer
por: Duan, Tinghui, et al.
Publicado: (2021)

Mechanisms of Cisplatin-Induced Apoptosis and of Cisplatin Sensitivity: Potential of BIN1 to Act as a Potent Predictor of Cisplatin Sensitivity in Gastric Cancer Treatment
por: Tanida, Satoshi, et al.
Publicado: (2012)

miR-7 Increases Cisplatin Sensitivity of Gastric Cancer Cells Through Suppressing mTOR
por: Xu, Ning, et al.
Publicado: (2017)

Midazolam increases cisplatin-sensitivity in non-small cell lung cancer (NSCLC) via the miR-194-5p/HOOK3 axis
por: Sun, Tingting, et al.
Publicado: (2021)

Hydroxylated Fatty Acids: The Role of the Sphingomyelin Synthase and the Origin of Selectivity
por: Sessa, Lucia, et al.
Publicado: (2021)

Hymenialdisine is Cytotoxic Against Cisplatin-Sensitive but Not Against Cisplatin-Resistant Cell Lines
por: Abdullah, Nada, et al.
Publicado: (2021)

Autophagy inhibitor chloroquine increases sensitivity to cisplatin in QBC939 cholangiocarcinoma cells by mitochondrial ROS
por: Qu, Xianzhi, et al.
Publicado: (2017)

Three Dimensional Structure Prediction of Fatty Acid Binding Site on Human Transmembrane Receptor CD36
por: Tarhda, Zineb, et al.
Publicado: (2013)

TRPC5 Channel Sensitivities to Antioxidants and Hydroxylated Stilbenes
por: Naylor, Jacqueline, et al.
Publicado: (2011)

PDCD5 transfection increases cisplatin sensitivity and decreases invasion in hepatic cancer cells
por: FAN, GUI-LING, et al.
Publicado: (2015)

Cisplatin-Resistant Gastric Cancer Cells Promote the Chemoresistance of Cisplatin-Sensitive Cells via the Exosomal RPS3-Mediated PI3K-Akt-Cofilin-1 Signaling Axis
por: Sun, Meng-Yao, et al.
Publicado: (2021)

miR-1271 enhances the sensitivity of colorectal cancer cells to cisplatin
por: Yao, Huixiang, et al.
Publicado: (2019)

Hsa‐circ‐0052001 promotes gastric cancer cell proliferation and invasion via the MAPK pathway
por: Xu, Qixuan, et al.
Publicado: (2022)

Knockdown of THOC1 reduces the proliferation of hepatocellular carcinoma and increases the sensitivity to cisplatin
por: Cai, Shijiao, et al.
Publicado: (2020)

Piperlongumine increases the sensitivity of bladder cancer to cisplatin by mitochondrial ROS
por: Pan, Xiaobo, et al.
Publicado: (2022)

Effect of Hydroxyl Groups Esterification with Fatty Acids on the Cytotoxicity and Antioxidant Activity of Flavones
por: Kubiak-Tomaszewska, Grażyna, et al.
Publicado: (2022)

Lactones from Unspecific Peroxygenase-Catalyzed In-Chain Hydroxylation of Saturated Fatty Acids
por: Ebrecht, Ana C., et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_64k4jpf011ov6mni5c8djs4oh6