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Blood neurofilament light chain as a biomarker of MS disease activity and treatment response

OBJECTIVE: To assess the value of blood neurofilament light chain (NfL) as a biomarker of recent, ongoing, and future disease activity and tissue damage and its utility to monitor treatment response in relapsing-remitting multiple sclerosis. METHODS: We measured NfL in blood samples from 589 patient...

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Detalles Bibliográficos
Autores principales: Kuhle, Jens, Kropshofer, Harald, Haering, Dieter A., Kundu, Uma, Meinert, Rolf, Barro, Christian, Dahlke, Frank, Tomic, Davorka, Leppert, David, Kappos, Ludwig
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6442011/
https://www.ncbi.nlm.nih.gov/pubmed/30737333
http://dx.doi.org/10.1212/WNL.0000000000007032