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CXCL6 Promotes Renal Interstitial Fibrosis in Diabetic Nephropathy by Activating JAK/STAT3 Signaling Pathway

In this study the role of CXCL6 in diabetic nephropathy (DN) was investigated. It was found to be overexpression in DN patients and DN rat model. And the expression of fibrosis-related cytokines was consistent with the expression of CXCL6. High glucose significantly increased the proliferation of ra...

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Detalles Bibliográficos
Autores principales: Sun, Meng-Yao, Wang, Su-Juan, Li, Xiao-Qin, Shen, Yu-Li, Lu, Jian-Rao, Tian, Xin-Hui, Rahman, Khalid, Zhang, Li-Jun, Nian, Hua, Zhang, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6442023/
https://www.ncbi.nlm.nih.gov/pubmed/30967776
http://dx.doi.org/10.3389/fphar.2019.00224