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Development and effects of tacrolimus-loaded nanoparticles on the inhibition of corneal allograft rejection

Tacrolimus has been widely applied to prevent organ rejection after transplantation. However, the conventional pharmaceutical formulation of tacrolimus limits its applications in ocular therapy due to its hydrophobicity and low corneal penetrability. We optimized tacrolimus-loaded methoxy poly (ethy...

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Detalles Bibliográficos
Autores principales: Wu, Qianni, Liu, Dong, Zhang, Xulin, Wang, Dongni, DongYe, Meimei, Chen, Wan, Lin, Duoru, Zhu, Fangming, Chen, Weirong, Lin, Haotian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6442111/
https://www.ncbi.nlm.nih.gov/pubmed/30895841
http://dx.doi.org/10.1080/10717544.2019.1582728