pH and reduction dual-responsive micelles based on novel polyurethanes with detachable poly(2-ethyl-2-oxazoline) shell for controlled release of doxorubicin

We describe a biodegradable amphiphilic polyurethane (PU) with disulfide bonds in the main chain [PEtOz-b-PU(SS)-b-PEtOz]. This multi-block PU was synthesized using poly (ε-caprolactone) diol (PCL-SS-PCL) and poly (2-ethyl-2-oxazoline) (PEtOz-OH) as soft segments, and bis (2-isocyanatoethyl) disulfi...

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Detalles Bibliográficos
Autores principales: Bu, Leran, Zhang, Hena, Xu, Kang, Du, Baixiang, Zhu, Caihong, Li, Yuling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6442156/
https://www.ncbi.nlm.nih.gov/pubmed/30895837
http://dx.doi.org/10.1080/10717544.2019.1580323

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6442156/
https://www.ncbi.nlm.nih.gov/pubmed/30895837
http://dx.doi.org/10.1080/10717544.2019.1580323

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