Design, synthesis, and apoptosis-promoting effect evaluation of novel pyrazole with benzo[d]thiazole derivatives containing aminoguanidine units

New pyrazole with benzo[d]thiazoles containing hydrazinecarboximidamide substituent was synthesised and evaluated for cytotoxicity and apoptotic activity using the MTT assay, flow cytometry, and Western blot analysis. Among the compounds studied, (E)-2-((1-(6-((4-fluorobenzyl)oxy)benzo[d]thiazol-2-y...

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Detalles Bibliográficos
Autores principales: Liu, Da Chuan, Gao, Mei Jia, Huo, Qiang, Ma, Tao, Wang, Ying, Wu, Cheng Zhu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6442160/
https://www.ncbi.nlm.nih.gov/pubmed/30915869
http://dx.doi.org/10.1080/14756366.2019.1591391

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6442160/
https://www.ncbi.nlm.nih.gov/pubmed/30915869
http://dx.doi.org/10.1080/14756366.2019.1591391

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