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Mass Spectrometry-based Absolute Quantification of 20S Proteasome Status for Controlled Ex-vivo Expansion of Human Adipose-derived Mesenchymal Stromal/Stem Cells

The proteasome controls a multitude of cellular processes through protein degradation and has been identified as a therapeutic target in oncology. However, our understanding of its function and the development of specific modulators are hampered by the lack of a straightforward method to determine t...

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Detalles Bibliográficos
Autores principales: Menneteau, Thomas, Fabre, Bertrand, Garrigues, Luc, Stella, Alexandre, Zivkovic, Dusan, Roux-Dalvai, Florence, Mouton-Barbosa, Emmanuelle, Beau, Mathilde, Renoud, Marie-Laure, Amalric, François, Sensébé, Luc, Gonzalez-de-Peredo, Anne, Ader, Isabelle, Burlet-Schiltz, Odile, Bousquet, Marie-Pierre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Biochemistry and Molecular Biology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6442357/
https://www.ncbi.nlm.nih.gov/pubmed/30700495
http://dx.doi.org/10.1074/mcp.RA118.000958