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Decreased Antibiotic Susceptibility Driven by Global Remodeling of the Klebsiella pneumoniae Proteome

Bacteria can circumvent the effect of antibiotics by transitioning to a poorly understood physiological state that does not involve conventional genetic elements of resistance. Here we examine antibiotic susceptibility with a Class A β-lactamase+ invasive strain of Klebsiella pneumoniae that was iso...

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Detalles Bibliográficos
Autores principales: Keasey, Sarah L., Suh, Moo-Jin, Das, Sudipto, Blancett, Candace D., Zeng, Xiankun, Andresson, Thorkell, Sun, Mei G., Ulrich, Robert G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Biochemistry and Molecular Biology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6442359/
https://www.ncbi.nlm.nih.gov/pubmed/30617156
http://dx.doi.org/10.1074/mcp.RA118.000739