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Regulation of T cell expansion by antigen presentation dynamics

An essential feature of the adaptive immune system is the proliferation of antigen-specific lymphocytes during an immune reaction to form a large pool of effector cells. This proliferation must be regulated to ensure an effective response to infection while avoiding immunopathology. Recent experimen...

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Detalles Bibliográficos
Autores principales: Mayer, Andreas, Zhang, Yaojun, Perelson, Alan S., Wingreen, Ned S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6442601/
https://www.ncbi.nlm.nih.gov/pubmed/30850527
http://dx.doi.org/10.1073/pnas.1812800116