Human pregnancy zone protein stabilizes misfolded proteins including preeclampsia- and Alzheimer’s-associated amyloid beta peptide

Protein misfolding underlies the pathology of a large number of human disorders, many of which are age-related. An exception to this is preeclampsia, a leading cause of pregnancy-associated morbidity and mortality in which misfolded proteins accumulate in body fluids and the placenta. We demonstrate...

Descripción completa

Detalles Bibliográficos
Autores principales: Cater, Jordan H., Kumita, Janet R., Zeineddine Abdallah, Rafaa, Zhao, Guomao, Bernardo-Gancedo, Ana, Henry, Amanda, Winata, Wendy, Chi, Mengna, Grenyer, Brin S. F., Townsend, Michelle L., Ranson, Marie, Buhimschi, Catalin S., Charnock-Jones, D. Stephen, Dobson, Christopher M., Wilson, Mark R., Buhimschi, Irina A., Wyatt, Amy R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2019
Materias:
PNAS Plus
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6442606/
https://www.ncbi.nlm.nih.gov/pubmed/30850528
http://dx.doi.org/10.1073/pnas.1817298116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6442606/
https://www.ncbi.nlm.nih.gov/pubmed/30850528
http://dx.doi.org/10.1073/pnas.1817298116

Ejemplares similares