A new BCR-ABL1 Drosophila model as a powerful tool to elucidate the pathogenesis and progression of chronic myeloid leukemia

The oncoprotein BCR-ABL1 triggers chronic myeloid leukemia. It is clear that the disease relies on constitutive BCR-ABL1 kinase activity, but not all the interactors and regulators of the oncoprotein are known. We describe and validate a Drosophila leukemia model based on inducible human BCR-ABL1 ex...

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Detalles Bibliográficos
Autores principales: Bernardoni, Roberto, Giordani, Giorgia, Signorino, Elisabetta, Monticelli, Sara, Messa, Francesca, Pradotto, Monica, Rosso, Valentina, Bracco, Enrico, Giangrande, Angela, Perini, Giovanni, Saglio, Giuseppe, Cilloni, Daniela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ferrata Storti Foundation 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6442973/
https://www.ncbi.nlm.nih.gov/pubmed/30409797
http://dx.doi.org/10.3324/haematol.2018.198267

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6442973/
https://www.ncbi.nlm.nih.gov/pubmed/30409797
http://dx.doi.org/10.3324/haematol.2018.198267

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