DICER1 somatic mutations strongly impair miRNA processing even in benign thyroid lesions

The alteration of miRNA processing is a driver event in several tumors including thyroid cancer. In particular, somatic DICER1 mutations, reported in follicular-patterned lesions, are shared by benign as well as malignant tumors. In the present study, we investigated the effects of alterations in th...

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Detalles Bibliográficos
Autores principales: Poma, Anello Marcello, Condello, Vincenzo, Denaro, Maria, Torregrossa, Liborio, Elisei, Rossella, Vitti, Paolo, Basolo, Fulvio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6442996/
https://www.ncbi.nlm.nih.gov/pubmed/30956758
http://dx.doi.org/10.18632/oncotarget.26639

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6442996/
https://www.ncbi.nlm.nih.gov/pubmed/30956758
http://dx.doi.org/10.18632/oncotarget.26639

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