Cargando…

DICER1 somatic mutations strongly impair miRNA processing even in benign thyroid lesions

The alteration of miRNA processing is a driver event in several tumors including thyroid cancer. In particular, somatic DICER1 mutations, reported in follicular-patterned lesions, are shared by benign as well as malignant tumors. In the present study, we investigated the effects of alterations in th...

Descripción completa

Detalles Bibliográficos
Autores principales:	Poma, Anello Marcello, Condello, Vincenzo, Denaro, Maria, Torregrossa, Liborio, Elisei, Rossella, Vitti, Paolo, Basolo, Fulvio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2019
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6442996/ https://www.ncbi.nlm.nih.gov/pubmed/30956758 http://dx.doi.org/10.18632/oncotarget.26639

Ejemplares similares

Using The Cancer Genome Atlas data to refine the 8th edition of the American Joint Committee on Cancer staging for papillary thyroid carcinoma
por: Poma, Anello Marcello, et al.
Publicado: (2020)

Hippo pathway affects survival of cancer patients: extensive analysis of TCGA data and review of literature
por: Poma, Anello Marcello, et al.
Publicado: (2018)

The 5(th) edition of WHO classification of tumors of endocrine organs: changes in the diagnosis of follicular-derived thyroid carcinoma
por: Basolo, Fulvio, et al.
Publicado: (2023)

Predictive Biomarkers in Thyroid Cancer
por: Macerola, Elisabetta, et al.
Publicado: (2022)

Response to Letter to the Editor From Green and Gosmanov: “Tall Cell Percentage Alone in PTC Without Aggressive Features Should not Guide Patients’ Clinical Management”
por: Viola, David, et al.
Publicado: (2022)

Molecular Alterations in Relation to Histopathological Characteristics in a Large Series of Pediatric Papillary Thyroid Carcinoma from a Single Institution
por: Macerola, Elisabetta, et al.
Publicado: (2021)

Clinical-Pathological and Molecular Evaluation of 451 NIFTP Patients from a Single Referral Center
por: Vignali, Paola, et al.
Publicado: (2022)

Outcomes of the Tall-Cell Variant of Papillary Thyroid Carcinoma in Patients with Different Ages: A 17-Year Mono-Institutional Experience
por: Proietti, Agnese, et al.
Publicado: (2023)

Molecular Genetics of Follicular-Derived Thyroid Cancer
por: Macerola, Elisabetta, et al.
Publicado: (2021)

Clinical–Pathological Features and Treatment Outcome of Patients With Hobnail Variant Papillary Thyroid Carcinoma
por: Poma, Anello Marcello, et al.
Publicado: (2022)

Fine-Needle Aspiration Cytology and Histological Types of Thyroid Cancer in the Elderly: Evaluation of 9070 Patients from a Single Referral Centre
por: Poma, Anello Marcello, et al.
Publicado: (2021)

Down-regulation of miR-7-5p and miR-548ar-5p predicts malignancy in indeterminate thyroid nodules negative for BRAF and RAS mutations
por: Macerola, Elisabetta, et al.
Publicado: (2022)

Salvage total thyroidectomy for amiodarone-induced thyrotoxicosis in a SARS-CoV-2 positive patient: results of the viral genome research on the pathology sample of this destructive thyroiditis
por: Cappellani, Daniele, et al.
Publicado: (2022)

Limited Accuracy of Pan-Trk Immunohistochemistry Screening for NTRK Rearrangements in Follicular-Derived Thyroid Carcinoma
por: Macerola, Elisabetta, et al.
Publicado: (2022)

RET mutation heterogeneity in primary advanced medullary thyroid cancers and their metastases
por: Romei, Cristina, et al.
Publicado: (2018)

Immune Transcriptome of Cells Infected with Enterovirus Strains Obtained from Cases of Type 1 Diabetes
por: Poma, Anello Marcello, et al.
Publicado: (2020)

Genetic Landscape of Somatic Mutations in a Large Cohort of Sporadic Medullary Thyroid Carcinomas Studied by Next-Generation Targeted Sequencing
por: Ciampi, Raffaele, et al.
Publicado: (2019)

RET Copy Number Alteration in Medullary Thyroid Cancer Is a Rare Event Correlated with RET Somatic Mutations and High Allelic Frequency
por: Ramone, Teresa, et al.
Publicado: (2020)

A six-gene panel to label follicular adenoma, low- and high-risk follicular thyroid carcinoma
por: Poma, Anello Marcello, et al.
Publicado: (2017)

Indeterminate Thyroid Nodules: From Cytology to Molecular Testing
por: Vignali, Paola, et al.
Publicado: (2023)

The italian consensus for the classification and reporting of thyroid cytology: Cytohistologic and molecular correlations on 37,371 nodules from a single institution
por: Torregrossa, Liborio, et al.
Publicado: (2022)

MicroRNA expression profiling of RAS-mutant thyroid tumors with follicular architecture: microRNA signatures to discriminate benign from malignant lesions
por: Macerola, E., et al.
Publicado: (2023)

RET mutated C-cells proliferate more rapidly than non-mutated neoplastic cells
por: Romei, Cristina, et al.
Publicado: (2021)

Higher RET Gene Expression Levels Do Not Represent anAlternative RET Activation Mechanism in Medullary Thyroid Carcinoma
por: Mulè, Chiara, et al.
Publicado: (2021)

Transcriptional changes in multiple endocrine organs from lethal cases of COVID-19
por: Poma, Anello Marcello, et al.
Publicado: (2023)

MON-524 Prospective Evaluation of Patients with Encapsulated Classical Variant of Papillary Thyroid Cancer and Noninvasive Follicular Thyroid Neoplasm with Papillary-Like Nuclear Features (NIFTP): Have They A Similar Prognosis?
por: Giani, Carlotta, et al.
Publicado: (2020)

The Molecular Signature More Than the Site of Localization Defines the Origin of the Malignancy
por: Matrone, Antonio, et al.
Publicado: (2019)

Core Needle Biopsy Can Early and Precisely Identify Large Thyroid Masses
por: Matrone, Antonio, et al.
Publicado: (2022)

Clinical, pathological and genetic features of anaplastic and poorly differentiated thyroid cancer: A single institute experience
por: Romei, Cristina, et al.
Publicado: (2018)

Impact of Advanced Age on the Clinical Presentation and Outcome of Sporadic Medullary Thyroid Carcinoma
por: Matrone, Antonio, et al.
Publicado: (2020)

Lung Recurrence of Papillary Thyroid Cancer Diagnosed With Antithyroglobulin Antibodies After 10 Years From Initial Treatment
por: Viola, David, et al.
Publicado: (2018)

Lenvatinib Administered via Nasogastric Tube in Poorly Differentiated Thyroid Cancer
por: Molinaro, Eleonora, et al.
Publicado: (2019)

Bilateral testicular metastases of medullary thyroid carcinoma in an adult male with multiple endocrine neoplasia 2A syndrome: case report and review of literature
por: Orsolini, Francesca, et al.
Publicado: (2022)

Immune Transcriptome of Cells Infected with Enterovirus Strains Obtained from Cases of Autoimmune Thyroid Disease
por: Poma, Anello Marcello, et al.
Publicado: (2021)

A nonfunctioning parathyroid carcinoma misdiagnosed as a follicular thyroid nodule
por: Cetani, Filomena, et al.
Publicado: (2015)

Metastasis of renal cell carcinoma to the parathyroid gland 16 years after radical nephrectomy: A case report
por: Torregrossa, Liborio, et al.
Publicado: (2016)

Active Surveillance in RET Gene Carriers Belonging to Families with Multiple Endocrine Neoplasia
por: Prete, Alessandro, et al.
Publicado: (2021)

Poorly Differentiated and Anaplastic Thyroid Cancer: Insights into Genomics, Microenvironment and New Drugs
por: Prete, Alessandro, et al.
Publicado: (2021)

Usefulness of second (131)I treatment in biochemical persistent differentiated thyroid cancer patients
por: Gambale, Carla, et al.
Publicado: (2023)

Sequencing of DICER1 in sarcomas identifies biallelic somatic DICER1 mutations in an adult-onset embryonal rhabdomyosarcoma
por: de Kock, Leanne, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_88n5383kr9emfcgrt22k4qio51