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Cortistatin binds to TNF-α receptors and protects against osteoarthritis
BACKGROUND: Osteoarthritis (OA) is a common degenerative disease, and tumor necrosis factor (TNF-α) is known to play a critical role in OA. Cortistatin (CST) is a neuropeptide discovered over 20 years ago, which plays a vital role in inflammatory reactions. However, it is unknown whether CST is inv...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6443028/ https://www.ncbi.nlm.nih.gov/pubmed/30826358 http://dx.doi.org/10.1016/j.ebiom.2019.02.035 |