Transposable elements drive widespread expression of oncogenes in human cancers

Transposable elements (TEs) are an abundant and rich genetic resource of regulatory sequences(1–3). Cryptic regulatory elements within TEs can be epigenetically reactivated in cancer to influence oncogenesis in a process termed onco-exaptation(4). However, the prevalence and impact of TE onco-exapta...

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Detalles Bibliográficos
Autores principales: Jang, Hyo Sik, Shah, Nakul M., Du, Alan Y., Dailey, Zea Z., Pehrsson, Erica C., Godoy, Paula M., Zhang, David, Li, Daofeng, Xing, Xiaoyun, Kim, Sungsu, O’Donnell, David, Gordon, Jeffrey I., Wang, Ting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6443099/
https://www.ncbi.nlm.nih.gov/pubmed/30926969
http://dx.doi.org/10.1038/s41588-019-0373-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6443099/
https://www.ncbi.nlm.nih.gov/pubmed/30926969
http://dx.doi.org/10.1038/s41588-019-0373-3

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