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Are interventions in reproductive medicine assessed for plausible and clinically relevant effects? A systematic review of power and precision in trials and meta-analyses

STUDY QUESTION: How much statistical power do randomised controlled trials (RCTs) and meta-analyses have to investigate the effectiveness of interventions in reproductive medicine? SUMMARY ANSWER: The largest trials in reproductive medicine are unlikely to detect plausible improvements in live birth...

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Detalles Bibliográficos
Autores principales: Stocking, K, Wilkinson, J, Lensen, S, Brison, D R, Roberts, S A, Vail, A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6443111/
https://www.ncbi.nlm.nih.gov/pubmed/30838395
http://dx.doi.org/10.1093/humrep/dez017