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Radiosensitization by enzalutamide for human prostate cancer is mediated through the DNA damage repair pathway

Radiation therapy is often combined with androgen deprivation therapy in the treatment of aggressive localized prostate cancer. However, castration-resistant disease may not respond to testosterone deprivation approaches. Enzalutamide is a second-generation anti-androgen with high affinity and activ...

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Detalles Bibliográficos
Autores principales: Sekhar, Konjeti R., Wang, Jian, Freeman, Michael L., Kirschner, Austin N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6443157/
https://www.ncbi.nlm.nih.gov/pubmed/30933998
http://dx.doi.org/10.1371/journal.pone.0214670