Cargando…
Radiosensitization by enzalutamide for human prostate cancer is mediated through the DNA damage repair pathway
Radiation therapy is often combined with androgen deprivation therapy in the treatment of aggressive localized prostate cancer. However, castration-resistant disease may not respond to testosterone deprivation approaches. Enzalutamide is a second-generation anti-androgen with high affinity and activ...
Autores principales: | Sekhar, Konjeti R., Wang, Jian, Freeman, Michael L., Kirschner, Austin N. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6443157/ https://www.ncbi.nlm.nih.gov/pubmed/30933998 http://dx.doi.org/10.1371/journal.pone.0214670 |
Ejemplares similares
-
Nucleophosmin Plays a Role in Repairing DNA Damage and Is a Target for Cancer Treatment
por: Sekhar, Konjeti R., et al.
Publicado: (2023) -
Targeting the DNA Damage Response and DNA Repair Pathways to Enhance Radiosensitivity in Colorectal Cancer
por: Deng, Siyao, et al.
Publicado: (2022) -
Targeting NPM1 in irradiated cells inhibits NPM1 binding to RAD51, RAD51 foci formation and radiosensitizes NSCLC
por: Traver, Geri, et al.
Publicado: (2020) -
Radiosensitivity in Non-Small-Cell Lung Cancer by MMP10 through the DNA Damage Repair Pathway
por: Bi, Yawei, et al.
Publicado: (2023) -
Knockdown GTSE1 enhances radiosensitivity in non–small‐cell lung cancer through DNA damage repair pathway
por: Lei, Xiao, et al.
Publicado: (2020)