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Investigation of somatic single nucleotide variations in human endogenous retrovirus elements and their potential association with cancer

Human endogenous retroviruses (HERVs) have been investigated for potential links with human cancer. However, the distribution of somatic nucleotide variations in HERV elements has not been explored in detail. This study aims to identify HERV elements with an over-representation of somatic mutations...

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Detalles Bibliográficos
Autores principales: Chang, Ting-Chia, Goud, Santosh, Torcivia-Rodriguez, John, Hu, Yu, Pan, Qing, Kahsay, Robel, Blomberg, Jonas, Mazumder, Raja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6443178/
https://www.ncbi.nlm.nih.gov/pubmed/30934003
http://dx.doi.org/10.1371/journal.pone.0213770