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Dynamic transcriptome profiles within spermatogonial and spermatocyte populations during postnatal testis maturation revealed by single-cell sequencing

Spermatogenesis is the process by which male gametes are formed from a self-renewing population of spermatogonial stem cells (SSCs) residing in the testis. SSCs represent less than 1% of the total testicular cell population in adults, but must achieve a stable balance between self-renewal and differ...

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Detalles Bibliográficos
Autores principales: Grive, Kathryn J., Hu, Yang, Shu, Eileen, Grimson, Andrew, Elemento, Olivier, Grenier, Jennifer K., Cohen, Paula E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6443194/
https://www.ncbi.nlm.nih.gov/pubmed/30893341
http://dx.doi.org/10.1371/journal.pgen.1007810