Histidine is selectively required for the growth of Myc‐dependent dedifferentiation tumours in the Drosophila CNS

Rewired metabolism of glutamine in cancer has been well documented, but less is known about other amino acids such as histidine. Here, we use Drosophila cancer models to show that decreasing the concentration of histidine in the diet strongly inhibits the growth of mutant clones induced by loss of N...

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Detalles Bibliográficos
Autores principales: Froldi, Francesca, Pachnis, Panayotis, Szuperák, Milán, Costas, Olivia, Fernando, Tharindu, Gould, Alex P, Cheng, Louise Y
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6443203/
https://www.ncbi.nlm.nih.gov/pubmed/30804004
http://dx.doi.org/10.15252/embj.201899895

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6443203/
https://www.ncbi.nlm.nih.gov/pubmed/30804004
http://dx.doi.org/10.15252/embj.201899895

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