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Histidine is selectively required for the growth of Myc‐dependent dedifferentiation tumours in the Drosophila CNS
Rewired metabolism of glutamine in cancer has been well documented, but less is known about other amino acids such as histidine. Here, we use Drosophila cancer models to show that decreasing the concentration of histidine in the diet strongly inhibits the growth of mutant clones induced by loss of N...
Autores principales: | Froldi, Francesca, Pachnis, Panayotis, Szuperák, Milán, Costas, Olivia, Fernando, Tharindu, Gould, Alex P, Cheng, Louise Y |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6443203/ https://www.ncbi.nlm.nih.gov/pubmed/30804004 http://dx.doi.org/10.15252/embj.201899895 |
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