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Endothelial dysfunction induces atherosclerosis: increased aggrecan expression promotes apoptosis in vascular smooth muscle cells

Endothelial dysfunction-induced lipid retention is an early feature of atherosclerotic lesion formation. Apoptosis of vascular smooth muscle cells (VSMCs) is one of the major modulating factors of atherogenesis, which accelerates atherosclerosis progression by causing plaque destabilization and rupt...

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Detalles Bibliográficos
Autores principales: Kim, Sang-Min, Huh, Jae-Wan, Kim, Eun-Young, Shin, Min-Kyung, Park, Ji-Eun, Kim, Seong Who, Lee, Wooseong, Choi, Bongkun, Chang, Eun-Ju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6443320/
https://www.ncbi.nlm.nih.gov/pubmed/30638179
http://dx.doi.org/10.5483/BMBRep.2019.52.2.282