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Acid sphingomyelinase-mediated blood-brain barrier disruption in aging

Although many studies have reported that the breakdown of the blood-brain barrier (BBB) represents one of the major pathological changes in aging, the mechanism underlying this process remains relatively unexplored. In this study, we described that acid sphingomyelinase (ASM) derived from endothelia...

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Detalles Bibliográficos
Autores principales: Park, Min Hee, Jin, Hee Kyung, Bae, Jae-sung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6443326/
https://www.ncbi.nlm.nih.gov/pubmed/30760383
http://dx.doi.org/10.5483/BMBRep.2019.52.2.033