Downregulation of Keap1 contributes to poor prognosis and Axitinib resistance of renal cell carcinoma via upregulation of Nrf2 expression

Kelch-like ECH-associated protein 1 (Keap1)/nuclear factor erythroid 2-related factor 2 (Nrf2) signaling has a protective effect on normal cells. A number of previous studies demonstrated that Keap1/Nrf2 signaling is associated with drug resistance in numerous tumors. The aim of the present study wa...

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Detalles Bibliográficos
Autores principales: Huang, Haipeng, Wu, Yunhong, Fu, Weijin, Wang, Xiaoming, Zhou, Liquan, Xu, Xiaolong, Huang, Fu, Wu, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6443340/
https://www.ncbi.nlm.nih.gov/pubmed/30896860
http://dx.doi.org/10.3892/ijmm.2019.4134

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6443340/
https://www.ncbi.nlm.nih.gov/pubmed/30896860
http://dx.doi.org/10.3892/ijmm.2019.4134

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