Molecular interaction of the antiviral compound CW-33 and its analogues with the NS2B-NS3 protease of the Japanese encephalitis virus

In a previous study from our group, a novel compound, namely CW-33 (ethyl 2-(3′,5′-dimethylanilino)-4-oxo-4,5-dihydrofuran-3-carboxylate) was identified that exhibited antiviral activity for Japanese encephalitis virus (JEV). The viral NS2B-NS3 serine protease serves an important role in cytoplasmic...

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Detalles Bibliográficos
Autores principales: Chen, Kuan-Chung, Lin, Yu-Fong, Huang, An-Cheng, Gao, Jing-Yang, Lin, Cheng-Wen, Lien, Jin-Cherng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6443346/
https://www.ncbi.nlm.nih.gov/pubmed/30816489
http://dx.doi.org/10.3892/ijmm.2019.4113

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6443346/
https://www.ncbi.nlm.nih.gov/pubmed/30816489
http://dx.doi.org/10.3892/ijmm.2019.4113

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