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Molecular interaction of the antiviral compound CW-33 and its analogues with the NS2B-NS3 protease of the Japanese encephalitis virus
In a previous study from our group, a novel compound, namely CW-33 (ethyl 2-(3′,5′-dimethylanilino)-4-oxo-4,5-dihydrofuran-3-carboxylate) was identified that exhibited antiviral activity for Japanese encephalitis virus (JEV). The viral NS2B-NS3 serine protease serves an important role in cytoplasmic...
Autores principales: | Chen, Kuan-Chung, Lin, Yu-Fong, Huang, An-Cheng, Gao, Jing-Yang, Lin, Cheng-Wen, Lien, Jin-Cherng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6443346/ https://www.ncbi.nlm.nih.gov/pubmed/30816489 http://dx.doi.org/10.3892/ijmm.2019.4113 |
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