Cargando…
Mlh1 deficiency increases the risk of hematopoietic malignancy after simulated space radiation exposure.
Cancer-causing genome instability is a major concern during space travel due to exposure of astronauts to potent sources of high-linear energy transfer (LET) ionizing radiation. Hematopoietic stem cells (HSCs) are particularly susceptible to genotoxic stress, and accumulation of damage can lead to H...
| Autores principales: | , , , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2018
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6443507/ https://www.ncbi.nlm.nih.gov/pubmed/30275527 http://dx.doi.org/10.1038/s41375-018-0269-8 |