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Targeting Aspergillus fumigatus Crf Transglycosylases With Neutralizing Antibody Is Relevant but Not Sufficient to Erase Fungal Burden in a Neutropenic Rat Model

Aspergillus fumigatus is an airborne opportunistic fungal pathogen responsible for severe infections. Among them, invasive pulmonary aspergillosis has become a major concern as mortality rates exceed 50% in immunocompromised hosts. In parallel, allergic bronchopulmonary aspergillosis frequently enco...

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Detalles Bibliográficos
Autores principales: Chauvin, David, Hust, Michael, Schütte, Mark, Chesnay, Adélaïde, Parent, Christelle, Moreira, Gustavo Marçal Schmidt Garcia, Arroyo, Javier, Sanz, Ana Belén, Pugnière, Martine, Martineau, Pierre, Chandenier, Jacques, Heuzé-Vourc’h, Nathalie, Desoubeaux, Guillaume
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6443627/
https://www.ncbi.nlm.nih.gov/pubmed/30972049
http://dx.doi.org/10.3389/fmicb.2019.00600