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Brain Edema Formation and Functional Outcome After Surgical Decompression in Murine Closed Head Injury Are Modulated by Acetazolamide Administration

Acetazolamide (ACZ), carbonic anhydrase inhibitor, has been successfully applied in several neurosurgical conditions for diagnostic or therapeutic purposes. Furthermore, neuroprotective and anti-edematous properties of ACZ have been postulated. However, its use in traumatic brain injury (TBI) is lim...

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Detalles Bibliográficos
Autores principales: Szczygielski, Jacek, Hubertus, Vanessa, Kruchten, Eduard, Müller, Andreas, Albrecht, Lisa Franziska, Mautes, Angelika E., Schwerdtfeger, Karsten, Oertel, Joachim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6443632/
https://www.ncbi.nlm.nih.gov/pubmed/30972006
http://dx.doi.org/10.3389/fneur.2019.00273