Chiral phenoxyacetic acid analogues inhibit colon cancer cell proliferation acting as PPARγ partial agonists

Peroxisome Proliferator-Activated Receptor γ (PPARγ) is an important sensor at the crossroad of diabetes, obesity, immunity and cancer as it regulates adipogenesis, metabolism, inflammation and proliferation. PPARγ exerts its pleiotropic functions upon binding of natural or synthetic ligands. The mo...

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Detalles Bibliográficos
Autores principales: Sabatino, Lina, Ziccardi, Pamela, Cerchia, Carmen, Muccillo, Livio, Piemontese, Luca, Loiodice, Fulvio, Colantuoni, Vittorio, Lupo, Angelo, Lavecchia, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6443668/
https://www.ncbi.nlm.nih.gov/pubmed/30931956
http://dx.doi.org/10.1038/s41598-019-41765-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6443668/
https://www.ncbi.nlm.nih.gov/pubmed/30931956
http://dx.doi.org/10.1038/s41598-019-41765-2

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