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LRP5, Bone Density, and Mechanical Stress: A Case Report and Literature Review

The Wnt-β-catenin pathway receptor, low-density lipoprotein receptor-related protein 5 (LRP5), is a known regulator of bone mineral density. It has been hypothesized that specific human polymorphisms in LRP5 impact bone density, in part, by altering the anabolic response of bone to mechanical loadin...

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Detalles Bibliográficos
Autores principales: Norwitz, Nicholas G., Mota, Adrian Soto, Misra, Madhusmita, Ackerman, Kathryn E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6443714/
https://www.ncbi.nlm.nih.gov/pubmed/30972028
http://dx.doi.org/10.3389/fendo.2019.00184