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Bio-ModelChecker: Using Bounded Constraint Satisfaction to Seamlessly Integrate Observed Behavior With Prior Knowledge of Biological Networks

The in silico study and reverse engineering of regulatory networks has gained in recognition as an insightful tool for the qualitative study of biological mechanisms that underlie a broad range of complex illness. In the creation of reliable network models, the integration of prior mechanistic knowl...

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Detalles Bibliográficos
Autores principales: Sedghamiz, Hooman, Morris, Matthew, Craddock, Travis J. A, Whitley, Darrell, Broderick, Gordon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6443719/
https://www.ncbi.nlm.nih.gov/pubmed/30972331
http://dx.doi.org/10.3389/fbioe.2019.00048