YAP inhibition enhances the differentiation of functional stem cell-derived insulin-producing β cells

Stem cell-derived insulin-producing beta cells (SC-β) offer an inexhaustible supply of functional β cells for cell replacement therapies and disease modeling for diabetes. While successful directed differentiation protocols for this cell type have been described, the mechanisms controlling its diffe...

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Detalles Bibliográficos
Autores principales: Rosado-Olivieri, Edwin A., Anderson, Kendall, Kenty, Jennifer H., Melton, Douglas A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6443737/
https://www.ncbi.nlm.nih.gov/pubmed/30931946
http://dx.doi.org/10.1038/s41467-019-09404-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6443737/
https://www.ncbi.nlm.nih.gov/pubmed/30931946
http://dx.doi.org/10.1038/s41467-019-09404-6

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