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YAP inhibition enhances the differentiation of functional stem cell-derived insulin-producing β cells

Stem cell-derived insulin-producing beta cells (SC-β) offer an inexhaustible supply of functional β cells for cell replacement therapies and disease modeling for diabetes. While successful directed differentiation protocols for this cell type have been described, the mechanisms controlling its diffe...

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Detalles Bibliográficos
Autores principales:	Rosado-Olivieri, Edwin A., Anderson, Kendall, Kenty, Jennifer H., Melton, Douglas A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6443737/ https://www.ncbi.nlm.nih.gov/pubmed/30931946 http://dx.doi.org/10.1038/s41467-019-09404-6

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